Publications - Texas A&M University Superfund Research Center

Analysis of per- and polyfluoroalkyl substances in Houston Ship Channel and Galveston Bay following a large-scale industrial fire using ion-mobility-spectrometry-mass spectrometry

READ 2022. Valdiviezo A, Aly NA, Luo Y-S, Cordova A, Casillas G, Foster M, Baker ES, Rusyn I. J Environ Sciences 115:350-362 May 2022. https://doi.org/10.1016/j.jes.2021.08.004. Available online 22 August 2021.

Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry

READ 2021. Roman-Hubers AT, Cordova AC, Aly NA, McDonald TJ, Lloyd DT, Wright FA, Baker ES, Chiu WA, Rusyn I. 2021. Energy Fuels. 2021 Jul 1;35(13):10529-10539. doi: 10.1021/acs.energyfuels.1c00892. Epub 2021 Jun 16.

Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis

READ 2019. Borowa-Mazgaj B, de Conti A, Tryndyak V, Steward CR, Jimenez L, Melnyk S, Seneshaw M, Mirshahi F, Rusyn I, Beland FA, Sanyal AJ, Pogribny IP. Toxicological Sciences, Volume 170, Issue 2, August 2019, Pages 273–282, https://doi.org/10.1093/toxsci/kfz110

Testing the efficacy of broad-acting sorbents for environmental mixtures using isothermal analysis, mammalian cells, and H. vulgaris

READ 2021. Wang M, Chen Z, Rusyn I, Phillips TD 2020.

J Hazard Mater. 2021 Apr 15;408:124425. doi: 10.1016/j.jhazmat.2020.124425. Epub 2020 Oct 28.

Quantitative In Vitro-to-In Vivo Extrapolation for Mixtures: A Case Study of Superfund Priority List Pesticides

READ 2021. Valdiviezo A, Luo Y-S, Chen Z, Chiu WA, Rusyn I. 2021. Toxicological Sciences, Volume 183, Issue 1, September 2021, Pages 60–69, https://doi.org/10.1093/toxsci/kfab076

Coping with post-hurricane mental distress: The role of neighborhood green space.

READ 2021. Li D, Newman G, Zhang T, Zhu R, Horney J 2021. Soc Sci Med. 2021 Jul;281:114084. doi: 10.1016/j.socscimed.2021.114084. Epub 2021 Jun 1.

Curated Data In – Trustworthy In Silico Models Out: The Impact of Data Quality on the Reliability of Artificial Intelligence Models as Alternatives to Animal Testing

READ 2021. Alves VM, Auerbach SS, Kleinstreuer N, Rooney JP, Muratov EN, Rusyn I, Tropsha A, Schmitt C 2021. Altern Lab Anim. 2021 Jul 7;2611929211029635. doi: 10.1177/02611929211029635. Online ahead of print.

Characterizing baseline legacy chemical contamination in urban estuaries for disaster-research through systematic evidence mapping: A case study

READ 2021. Camargo KM, Foster M, Buckingham B, McDonald TJ, Chiu WA 2021. Chemosphere. 2021 Oct;281:130925. doi: 10.1016/j.chemosphere.2021.130925. Epub 2021 May 22.

Multiobjective Optimization of Mixed-Integer Linear Programming Problems: A Multiparametric Optimization Approach

READ 2021. Pappas I, Avraamidou S, Katz J, Burnak B, Beykal B, Türkay M, Pistikopoulos EN 2021. Ind Eng Chem Res. 2021 Jun 16;60(23):8493-8503. doi: 10.1021/acs.iecr.1c01175. Epub 2021 Jun 4.

Bi-level Mixed-Integer Data-Driven Optimization of Integrated Planning and Scheduling Problems

READ 2021. Beykal B, Avraamidou S, Pistikopoulos EN 2021. ESCAPE. 2021;50:1707-1713. doi: 10.1016/b978-0-323-88506-5.50265-5. Epub 2021 Jul 18.

Web of Science-Based Green Infrastructure: A Bibliometric Analysis in CiteSpace

READ 2021. Shao H, Kim G, Li Q, Newman G 2021. Land (Basel). 2021 Jul;10(7);711. doi: 10.3390/land10070711. Epub 2021 Jul 6.

Preliminary Study of Lead-Contaminated Drinking Water in Public Parks-An Assessment of Equity and Exposure Risks in Two Texas Communities

READ 2021. Fawkes L, Sansom G 2021. Int J Environ Res Public Health. 2021 Jun 14;18(12);6443. doi: 10.3390/ijerph18126443.

Predicting the Estrogen Receptor Activity of Environmental Chemicals by Single-Cell Image Analysis and Data-driven Modeling

READ 2021. Ganesh HS, Beykal B, Szafran AT, Stossi F, Zhou L, Mancini MA, Pistikopoulos EN 2021. ESCAPE. 2021;50:482-486. doi: 10.1016/b978-0-323-88506-5.50076-0. Epub 2021 Jul 18.

Disparate access to nutritional food; place, race and equity in the United States

READ 2021. Sansom G, Hannibal B 2021. BMC Nutr. 2021 Jun 29;7(1):29. doi: 10.1186/s40795-021-00434-2.

A new approach method for characterizing inter-species toxicodynamic variability

READ 2021. Burnett SD, Karmakar M, Murphy WJ, Chiu WA, Rusyn I 2021. J Toxicol Environ Health A. 2021 Aug 24:1-20. doi: 10.1080/15287394.2021.1966861. Online ahead of print.

Molecular mechanisms of environmental toxin cadmium at the feto-maternal interface investigated using an organ-on-chip (FMi-OOC) model

READ 2021. Kim S, Richardson L, Radnaa E, Chen Z, Rusyn I, Menon R, Han A. J Hazard Mater. 2021. Aug 2;422:126759. doi: 10.1016/j.jhazmat.2021.126759. Online ahead of print.

Combining Experimental Isotherms, Minimalistic Simulations, and a Model to Understand and Predict Chemical Adsorption onto Montmorillonite Clays

READ 2021. Orr AA, Wang M, Beykal B, Ganesh HS, Hearon SE, Pistikopoulos EN, Phillips TD, Tamamis P 2021. ACS Omega. 2021. May 26;6(22):14090-14103. doi: 10.1021/acsomega.1c00481. eCollection 2021 Jun 8.

Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors

READ 2021. Burnett SD, Blanchette AD, Chiu WA, Rusyn I 2021. Chem Res Toxicol. 2021 Aug 27. doi: 10.1021/acs.chemrestox.1c00203. Online ahead of print.

Biosensor applications in Galveston Bay: Implications for disaster research

READ 2021. Camargo K, Vogelbein MA, Horney JA, Dellapenna TM, Knap AH, Sericano JL, Wade TL, McDonald TJ, Chiu WA, Unger MA. 2021. Environ Res 2021; Aug19;111893. doi: 10.1016/j.envres.2021.111893. Online ahead of print.

Spatial Distribution of Polycyclic Aromatic Hydrocarbon Contaminants after Hurricane Harvey in a Houston Neighborhood

READ 2021. Sansom GT, Kirsch KR, Casillas GA, Camargo K, Wade TL, Knap AH, Baker ES, Horney JA 2021. J Health Pollut 2021; 11 (29):210308. doi: 10.5696/2156-9614-11.29.210308. eCollection 2021 Mar.

Spatial and temporal distribution of surface water contaminants in the Houston Ship Channel after the Intercontinental Terminal Company Fire

READ 2021. Jang S, McDonald TJ, Bhandari S, Rusyn I, Chiu WA 2021. J Expo Sci Environ Epidemiol 2021 Jun 2. doi: 10.1038/s41370-021-00343-3. Online ahead of print.

Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity

READ 2021. Rusyn I, Arzuaga X, Cattley RC, Corton JC, Ferguson SS, Godoy P, Guyton KZ, Kaplowitz N, Khetani SR, Roberts R, Roth RA, Smith MT 2021. Hepatology 2021 Jun 9. doi: 10.1002/hep.31999. Online ahead of print.

Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks.

READ 2021. Aly NA, Casillas G, Luo YS, McDonald TJ, Wade TL, Zhu R, Newman G, Lloyd D, Wright FA, Chiu WA, Rusyn I 2021. J Expo Sci Environ Epidemiol 2021 Apr 24. doi: 10.1038/s41370-021-00325-5. Online ahead of print.

Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments

READ 2021. Odenkirk MT, Reif DM, Baker ES 2021. Anal Chem 2021; 93 (22):7763-7773. doi: 10.1021/acs.analchem.0c04850. Epub 2021 May 24.

Quantitative in Vitro-to-in Vivo Extrapolation for Mixtures: A Case Study of Superfund Priority List Pesticides

READ 2021. Valdiviezo A, Luo YS, Chen Z, Chiu WA, Rusyn I 2021. Toxicol Sci 2021 Jun 17;kfab076. doi: 10.1093/toxsci/kfab076. Online ahead of print.

Exposure and Toxicity Characterization of Chemical Emissions and Chemicals in Products: Global Recommendations and Implementation in USEtox

READ 2021. Fantke P, Chiu WA, Aylward L, Judson R, Huang L, Jang S, Gouin T, Rhomberg L, Aurisano N, McKone T, Jolliet O 2021. Int J Life Cycle Assess 2021; 26 (5):899-915. doi: 10.1007/s11367-021-01889-y. Epub 2021 Apr 5.

Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male Mice

READ 2021. Dalaijamts C, Cichocki JA, Luo YS, Rusyn I, Chiu WA 2021. Toxicol Sci 2021 Aug 3;182(2):168-182. doi: 10.1093/toxsci/kfab057.

Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization

READ 2021. Burnett SD, Blanchette AD, Chiu WA, Rusyn I 2021. Expert Opin Drug Metab Toxicol 2021 Aug;17(8):887-902. doi: 10.1080/17425255.2021.1894122. Epub 2021 Mar 8.

Risk Characterization and Probabilistic Concentration-Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic in Vitro Human Stem Cell Assays

READ 2021. Hsieh NH, Chen Z, Rusyn I, Chiu WA 2021. Environ Health Perspect. 2021 Jan;129(1):17004. doi: 10.1289/EHP7600. Epub 2021 Jan 4.

Decreased bioavailability of aminomethylphosphonic acid (AMPA) in genetically modified corn with activated carbon or calcium montmorillonite clay inclusion in soil

READ 2021. Hearon SE, Wang M, McDonald TJ, Phillips TD 2021. J Environ Sci (China). 2021 Feb;100:131-143. doi: 10.1016/j.jes.2020.06.029. Epub 2020 Jul 27.

Enhanced adsorption of per- and polyfluoroalkyl substances (PFAS) by edible, nutrient-amended montmorillonite clays

READ 2021. Wang M, Orr AA, Jakubowski JM, Bird KE, Casey CM, Hearon SE, Tamamis P, Phillips TD 2021. Water Res. 2021 Jan 1;188:116534. doi: 10.1016/j.watres.2020.116534. Epub 2020 Oct 20.

Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS)

READ 2021. Sakolish C, Reese CE, Luo YS, Valdiviezo A, Schurdak ME, Gough A, Taylor DL, Chiu WA, Vernetti LA, Rusyn I 2021. Toxicology. 2021 Jan 30;448:152651. doi: 10.1016/j.tox.2020.152651. Epub 2020 Dec 8.

From Pesticides to Per- and Polyfluoroalkyl Substances: An Evaluation of Recent Targeted and Untargeted Mass Spectrometry Methods for Xenobiotics

READ 2021. Dodds JN, Alexander NLM, Kirkwood KI, Foster MR, Hopkins ZR, Knappe DRU, Baker ES 2021. Anal Chem. 2021 Jan 12;93(1):641-656. doi: 10.1021/acs.analchem.0c04359. Epub 2020 Nov 2.

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning

READ 2021. Marvel SW, House JS, Wheeler M, Song K, Zhou YH, Wright FA, Chiu WA, Rusyn I, Motsinger-Reif A, Reif DM 2021. Environ Health Perspect. 2021 Jan;129(1):17701. doi: 10.1289/EHP8690. Epub 2021 Jan 5.

Risk Characterization of Environmental Samples Using In Vitro Bioactivity and Polycyclic Aromatic Hydrocarbon Concentrations Data

READ 2021. Chen Z, Lloyd D, Zhou YH, Chiu WA, Wright FA, Rusyn I 2021. Toxicol Sci. 2021 Jan 6;179(1):108-120. doi: 10.1093/toxsci/kfaa166.

Polycyclic aromatic hydrocarbons (PAHs) cycling and fates in Galveston Bay, Texas, USA

READ 2020. Rowe GT, Fernando H, Elferink C, Ansari GAS, Sullivan J, Heathman T, Quigg A, Petronella Croisant S, Wade TL, Santschi PH 2020 PLoS One. 2020 Dec 28;15(12):e0243734. doi: 10.1371/journal.pone.0243734. eCollection 2020.

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

READ 2020. Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A 2020. ALTEX. 2020;37(3):365-394. doi: 10.14573/altex.2001241. Epub 2020 Feb 28.

From Prevention to Disease Perturbations: A Multi-Omic Assessment of Exercise and Myocardial Infarctions

READ 2020. Odenkirk MT, Stratton KG, Bramer LM, Webb-Robertson BM, Bloodsworth KJ, Monroe ME, Burnum-Johnson KE, Baker ES 2020. Biomolecules. 2020 Dec 30;11(1):40. doi: 10.3390/biom11010040.

Polycyclic aromatic hydrocarbon status in post-hurricane Harvey sediments: Considerations for environmental sampling in the Galveston Bay/Houston Ship Channel region

READ 2020. Camargo K, Sericano JL, Bhandari S, Hoelscher C, McDonald TJ, Chiu WA, Wade TL, Dellapenna TM, Liu Y, Knap AH 2020. Mar Pollut Bull. 2021 Jan;162:111872. doi: 10.1016/j.marpolbul.2020.111872. Epub 2020 Nov 28.

Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH

READ 2020. Mistry RM, Singh PK, Mancini MG, Stossi F, Mancini MA 2020. J Vis Exp. 2020 Sep 20;(163). doi: 10.3791/61680

Rapid Characterization of Emerging Per- and Polyfluoroalkyl Substances in Aqueous Film-Forming Foams Using Ion Mobility Spectrometry-Mass Spectrometry

READ 2020. Luo YS, Aly NA, McCord J, Strynar MJ, Chiu WA, Dodds JN, Baker ES, Rusyn I 2020. Environ Sci Technol. 2020 Dec 1;54(23):15024-15034. doi: 10.1021/acs.est.0c04798. Epub 2020 Nov 11.

How tropical cyclone flooding caused erosion and dispersal of mercury-contaminated sediment in an urban estuary: The impact of Hurricane Harvey on Buffalo Bayou and the San Jacinto Estuary, Galveston Bay, USA

READ 2020. Dellapenna TM, Hoelscher C, Hill L, Al Mukaimi ME, Knap A 2020. Sci Total Environ. 2020 Dec 15;748:141226. doi: 10.1016/j.scitotenv.2020.141226. Epub 2020 Jul 31

Insights into the interactions of bisphenol and phthalate compounds with unamended and carnitine-amended montmorillonite clays

READ 2020. Orr AA, He S, Wang M, Goodall A, Hearon SE, Phillips TD, Tamamis P 2020. Comput Chem Eng. 2020 Dec 5;143:107063. doi: 10.1016/j.compchemeng.2020.107063. Epub 2020 Aug 21.

Unveiling molecular signatures of preeclampsia and gestational diabetes mellitus with multi-omics and innovative cheminformatics visualization tools

READ 2020. Odenkirk MT, Stratton KG, Gritsenko MA, Bramer LM, Webb-Robertson BM, Bloodsworth KJ, Weitz KK, Lipton AK, Monroe ME, Ash JR, Fourches D, Taylor BD, Burnum-Johnson KE, Baker ES 2020. Mol Omics. 2020 Dec 1;16(6):521-532. doi: 10.1039/d0mo00074d. Epub 2020 Sep 23.

Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems

READ 2020. Odenkirk MT, Zin PPK, Ash JR, Reif DM, Fourches D, Baker ES 2020. Analyst. 2020 Nov 9;145(22):7197-7209. doi: 10.1039/d0an01638a.

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: monitoring county level vulnerability

READ 2020. Marvel S, House J, Wheeler M, Song K, Zhou Y, Wright F, Chiu W, Rusyn I, Motsinger-Reif A, Reif DM 2020. medRxiv. 2020 Aug 13;2020.08.10.20169649. doi: 10.1101/2020.08.10.20169649. Preprint

Well-tempered MCMC simulations for population pharmacokinetic models

READ 2020. Bois FY, Hsieh NH, Gao W, Chiu WA, Reisfeld B 2020. J Pharmacokinet Pharmacodyn. 2020 Dec;47(6):543-559. doi: 10.1007/s10928-020-09705-0. Epub 2020 Jul 31.

Recent Advances in Probabilistic Dose-Response Assessment to Inform Risk-Based Decision Making

READ 2020. Chiu WA, Paoli GM 2020. Risk Anal. 2020 Sep 23. doi: 10.1111/risa.13595. Online ahead of print.

Single-Cell Distribution Analysis of AR Levels by High-Throughput Microscopy in Cell Models: Application for Testing Endocrine-Disrupting Chemicals

READ 2020. Stossi F, Mistry RM, Singh PK, Johnson HL, Mancini MG, Szafran AT, Mancini MA 2020. SLAS Discov. 2020 Aug;25(7):684-694. doi: 10.1177/2472555220934420. Epub 2020 Jun 18.

A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals

READ 2020. Szafran AT, Bolt MJ, Obkirchner CE, Mancini MG, Helsen C, Claessens F, Stossi F, Mancini MA 2020. SLAS Discov. 2020 Aug;25(7):695-708. doi: 10.1177/2472555220922917. Epub 2020 May 11.

Integrating Prediction and Performance Models into Scenario-based Resilient Community Design

READ 2020. Newman G, Kim Y, Joshi K, Liu J 2020. J Digit Landsc Archit. 2020;5:510-520.

Urban regeneration: Community engagement process for vacant land in declining cities

READ 2020. Kim G, Newman G, Jiang B 2020. Cities. 2020 Jul;102:102730. doi: 10.1016/j.cities.2020.102730. Epub 2020 Apr 27.

Tight sorption of arsenic, cadmium, mercury, and lead by edible activated carbon and acid-processed montmorillonite clay

READ 2020. Wang M, Bera G, Mitra K, Wade TL, Knap AH, Phillips TD 2020. Environ Sci Pollut Res Int. 2021 Feb;28(6):6758-6770. doi: 10.1007/s11356-020-10973-z. Epub 2020 Oct 2.

Metabolite collision cross section prediction without energy-minimized structures

READ 2020. Soper-Hopper MT, Vandegrift J, Baker ES, Fernández FM 2020. Analyst. 2020 Aug 21;145(16):5414-5418. doi: 10.1039/d0an00198h. Epub 2020 Jun 25.

Integrated Modeling of Transfer Learning and Intelligent Heuristic Optimization for Steam Cracking Process

READ 2020. Bi K, Beykal B, Avraamidou S, Pappas I, Pistikopoulos EN, Qiu T 2020. Ind Eng Chem Res. 2020 Sep 16;59(37):16357-16367. doi: 10.1021/acs.iecr.0c02657. Epub 2020 Aug 20.

Application of a unified probabilistic framework to the dose-response assessment of acrolein

READ 2020. Blessinger T, Davis A, Chiu WA, Stanek J, Woodall GM, Gift J, Thayer KA, Bussard D 2020. Environ Int. 2020 Oct;143:105953. doi: 10.1016/j.envint.2020.105953. Epub 2020 Aug 5.

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms

READ 2020. Mukherjee R, Beykal B, Szafran AT, Onel M, Stossi F, Mancini MG, Lloyd D, Wright FA, Zhou L, Mancini MA, Pistikopoulos EN 2020. PLoS Comput Biol. 2020 Sep 24;16(9):e1008191. doi: 10.1371/journal.pcbi.1008191. eCollection 2020 Sep.