CalEPA OEHHA Event | May 2024

New Tools and Approaches to Support Decision-Making in Inhalation Toxicology WORKSHOP

New Tools and Approaches to Support Decision-Making in Inhalation Toxicology

Thursday, May 23, 2024 | 9 a.m. – 4:00 p.m. (US Pacific Time Zone)
Coastal Hearing Room | CalEPA Headquarters Building | 1001 I St. | Sacramento, CA 95814

Join the California EPA Office of Environmental Health Hazard Assessment (OEHHA) and the Texas A&M Superfund Research Center to explore the use of new approach methodologies in inhalation toxicology and air toxics risk assessment.

The workshop will focus on read-across methods and high-throughput tests to support decision-making for air toxics that lack traditional assessments.

Speakers and panelists: Lauren Zeise (OEHHA), Ivan Rusyn (Texas A&M), Kannan Krishnan (OEHHA), David Dorman (NCSU), Allison Phillips (US EPA), Sylvia Escher (FITEM, Hannover), Jennifer Sass (NRDC), James Armitage (AES Inc., Ottawa), Xiaoqing Chang (Inotiv, supporting NICEATM), Weihsueh Chiu (Texas A&M), and Anatoly Soshilov (OEHHA)


(US Pacific)
9:00–9:10 a.m.Welcome and introductionsLauren Zeise (OEHHA)
9:10–9:20 a.m.Workshop overview and charge to the participantsIvan Rusyn
(Texas A&M University)
9:20–9:40 a.m.Assessing health risks of air toxics in California: Overview and needsKannan Krishnan (OEHHA)
9:40–10:10 a.m.Challenges of inhalation toxicology and where might NAMs fit in?David Dorman (North Carolina State University)
10:15–10:30 a.m.BREAK
10:30–11:00 a.m.Use of read-across to develop provisional health guidance valuesAllison Phillips (US EPA)
11:00–11:30 a.m.Tiered testing and assessment strategy using NAMs data to inform decision-making on inhalation exposuresSylvia Escher (Fraunhofer Institute for Toxicology and Experimental Medicine)
11:30 a.m.–12:30 p.m.Moderated panel discussion
[David Dorman, Allison Phillips, Sylvia Escher, and Jennifer Sass (NRDC)]
Moderated by Ivan Rusyn
(Texas A&M University)
12:30–1:30 p.m.LUNCH
1:30–2:00 p.m.Dosimetry considerations for in vitro assays of volatile chemicalsJames Armitage (AES Inc.)
2:00–2:30 p.m.IVIVE approaches to studies of inhalation toxicantsXiaoqing Chang (Inotiv, supporting NICEATM)
2:30–2:45 p.m.BREAK
2:45–3:45 p.m.Moderated panel discussion
[James Armitage, Xiaoqing Chang, and Jennifer Sass (NRDC)]
Moderated by Weihsueh Chiu
(Texas A&M University)
3:45–4:00 p.m.Closing remarksAnatoly Soshilov (OEHHA)